(= PGI2)
Unstable prostaglandin released by mast cells and endothelium, a potent inhibitor of platelet aggregation; also causes vasodilation and increased vascular permeability. Release enhanced by bradykinin.

Dictionary of molecular biology. 2004.

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  • prostacyclin — [präs΄tə sī′klin] n. [< PROSTAGLANDIN + CYCL(O) + IN1] a derivative of prostaglandins that forms in the walls of blood vessels, prevents blood clots, and, usually, dilates blood vessels: cf. THROMBOXANE …   English World dictionary

  • Prostacyclin — drugbox IUPAC name = 5 [7 hydroxy 8 (3 hydroxyoct 1 enyl) 4 oxabicyclo [3.3.0] oct 3 ylidene] pentanoic acid width=200px CAS number = 35121 78 9 ATC prefix = B01 ATC suffix = AC09 ATC supplemental = PubChem = 114805 DrugBank = APRD00949 C=20 |… …   Wikipedia

  • Prostacyclin — Strukturformel Allgemeines Freiname Epoprostenol And …   Deutsch Wikipedia

  • Prostacyclin receptor — (or prostaglandin I2 receptor) is a receptor for prostacyclin. PBB Summary section title = summary text = It is a member of the G protein coupled receptor family. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium,… …   Wikipedia

  • Prostacyclin-Rezeptor — Masse/Länge Primärstruktur 383 Aminosäuren …   Deutsch Wikipedia

  • Prostacyclin synthase — protein Name=prostaglandin I2 (prostacyclin) synthase width=250 caption=Cartoon diagram of human prostacyclin synthase. Heme group visible at center. From PDB|2IAG HGNCid=9603 Symbol=PTGIS AltSymbols= EntrezGene=5740 OMIM=601699 RefSeq=NM 000961… …   Wikipedia

  • prostacyclin — noun Etymology: prosta (as in prostaglandin) + cycl + 1 in Date: 1976 a prostaglandin that is a metabolite of arachidonic acid, inhibits platelet aggregation, and dilates blood vessels …   New Collegiate Dictionary

  • prostacyclin — /pros teuh suy klin/, n. Biochem. a prostaglandin, C20H32O5, that specifically inhibits the formation of blood clots. [1975 80; PROSTA(TE) + CYCL(IC) + IN2, on the model of PROSTAGLANDIN] * * * …   Universalium

  • prostacyclin — noun A prostaglandin produced in the walls of blood vessels; it acts as a vasodilator and inhibits the aggregation of platelets …   Wiktionary

  • prostacyclin — A potent natural inhibitor of platelet aggregation and a powerful vasodilator. SYN: epoprostenol, epoprostenol sodium. * * * pros·ta·cy·clin .präs tə sī klən n a prostaglandin that is a metabolite of arachidonic acid, inhibits aggregation of… …   Medical dictionary

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